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DO
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It
is pretty common that couples and individuals begin looking into
Assisted Reproduction when they went through a number of failed IVF
cycles. Not only it is emotionally and psychologically damaging, it may
be financially draining. In the USA, the average IVF cycle may cost up
to $20,000. So 4-5 IVF cycles may leave the family financially broke.
There
are indeed very clear predictors of IVF success. Two major factors need
to be considered prior to beginning an IVF cycle:
IVF
FAILURE FACTOR 1: Egg Quality that is translated into age
factor and antral
follicle count or base
follicul count
IVF
FAILURE FACTOR 2: Implantation Failure
According
to the research done by Advanced
Fertility Center of Chicago in
Chicago,IL, IVF outcomes can be predicted. Female
age is very important
considering success of getting pregnant via IVF. The real issue is egg
quantity and quality - which
translates over to embryo
quality
after fertilization. Increased infertility with age is a well
documented problem and very apparent in modern society. As women wait
longer to have children, a higher percentage of couples have fertility
problems because of the quality of the eggs, and other issues that
affect fertility and are more common in older women. Women's
liberation has brought many advantages to women. However, as women
increasingly delay childbearing, our society has done a very poor job
of educating people about the decline in female fertility with
increasing age. Too many couples learn about the impact of age when it
could already be too late for them. Many couples end up needing
advanced treatments such as IVF to help overcome the age related
decline in egg quality. If they had tried to have a baby years sooner,
good old-fashioned "sex in the bedroom" could have built the family.
The
American Society for Reproductive Medicine said it well: "As women
delay childbearing, there is now an unrealistic expectation that
medical science can undo the effects of aging". Successful pregnancy
outcome with treatment is very much related to female age - when using
the woman's own eggs. When donor
eggs are being used, the age
of the egg donor is the
important issue.
With
egg donation, the age of the recipient woman does not seem to affect
the chance for success.
This means that the age of the egg is very important, but the age of
the uterus is not. See the graph below for more on this.
The age of the male partner does not appear to matter nearly as much.
This is related to the fact that all of a woman's eggs are present at
birth. They can not divide or be "resupplied", whereas sperm are
produced constantly after puberty in men. Eggs age over time, while new
sperm are constantly coming off the production line. Sperm from older
men does not usually have a substantially reduced fertilizing potential
as compared to sperm from younger men. However, older men often have
less interest in frequent intercourse, which can be a factor in chances
for conception.
Not
only we can predict the IVF for a give age group, there are some tests
that will allow to calculate how many eggs will be retrieved for the
patients by using Antral
Follicle Test.
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DO I
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