IVF SUCCESS RATE

The delivery rate or "take home baby rate" is the only real measure of success. Patients should be aware, however, that some clinics define "success" as any positive pregnancy test or any pregnancy, even if miscarried or ectopic. These "successes" are irrelevant to patients desiring a baby. To put these figures into perspective, studies have shown that the rate of pregnancy in couples with proven fertility in the past is only about 20% per cycle. Therefore, although a figure of 28% may sound low, it is greater than the chance that a fertile couple will conceive in any given cycle. Success varies with many factors.

The age of the woman is the most important factor, when women are using their own eggs. Success rates decline as women age, and success rates drop off even more dramatically after about age 37. Part of this decline is due to a lower chance of getting pregnant from ART, and part is due to a higher risk of miscarriage with increasing age, especially over age 40.

The major hurdles to success are implantation after embryo transfer and early pregnancy loss. We still do not understand all the factors that influence the potential of embryos to implant and produce successful pregnancies.

The rate of early pregnancy loss is slightly, but not significantly, higher with ART compared to spontaneous conception.

IVF STATISTICS

According to the USA Department of Health data,the 127,977 ART cycles performed by 411 clinics resulted in 36,760 life birth (delivering one or more living infants) and 49,458 infants.

Twin delivery - About 30% of ART deliveries are twin deliveries, versus 1-2% of spontaneous pregnancies.

More than twin delivery - Less than 5%.

Couples who have achieved an ART pregnancy and delivery in the past have a slightly increased likelihood of success for future treatment.

Fresh IVF cycles using non-donor Eggs or Embryos:

Average Clinical Pregnancy rate: 33,7% for all age groups

Women age 20-32: Average Clinical Pregnancy rate: 40-42%, Live birth rate 38-40 %

Women age 33-34: Average Clinical Pregnancy rate: 40%, Live birth rate 38 %

Women age 35-36: Average Clinical Pregnancy rate: 38%, Live birth rate 35 %

Women age over 36: Dramatic decline to: 24-25%, Live birth rate 18-20 %

Women age 41: Average Clinical Pregnancy rate: 20-22%, Live birth rate 15 %

Women age 42-46: Dramatic decline to: 1-10%, Live birth rate 0-2 %

Frozen IVF cycles using non-donor Eggs or Embryos:

Live birth rate: 27,7% per transfer

EGG DONOR SUCCESS RATE

Fresh IVF cycles using Donor Eggs or Embryos:

Average Live birth rate: 51% for all age groups

Women age 20-49: Live birth rate 50-55%

Women over: Slight decline with age

Frozen IVF cycles using Donor Eggs or Embryos:

Average Live birth rate: 30.5% for all age groups

ICSI SUCCESS RATE

Women age <35: With ICSI - Live birth rate 41.0%

Women age <35: Without ICSI - Live birth rate 42.2%

Women age 35-37: With ICSI - Live birth rate 35.9%

Women age 35-37: Without ICSI - Live birth rate 33.6%

Women age 38-40: With ICSI - Live birth rate 22.7%

Women age 38-40: Without ICSI - Live birth rate 25.9%

Women age 41-42: With ICSI - Live birth rate 22.7%

Women age 41-42: Without ICSI - Live birth rate 25.9%

Women age >42: With ICSI - Live birth rate 6.1%

Women age >42: Without ICSI - Live birth rate 5.6%

Women age 42-46: Dramatic decline to: 1-10%, Live birth rate 0-2 %

IVF SUCCESS RATES